HomeCoursesMEDSCI 204: Pharmacology and ToxicologyLecture 25 Lecture 25 1. What is the first aspect of clinical trial design? Assignment (randomized, balanced, stratified by individual factors)What is the first aspect of clinical trial design? ==Assignment (randomized, balanced, stratified by individual factors) 2. What is the 2nd aspect of trial design? Blinding (open, single blind, double blind, double dummy)What is the 2nd aspect of trial design?== Blinding (open, single blind, double blind, double dummy) 3. What is the 3rd aspect of trial design?= =Comparison (active, inactive/placebo sham, standard treatment) What is the 3rd aspect of trial design?= =Comparison (active, inactive/placebo sham, standard treatment) 4. What is the most common comparison? active vs inactiveWhat is the most common comparison?== active vs inactive 5. What is the forth aspect of trial design? Sequence (parallel, crossover, titration)What is the forth aspect of trial design?== Sequence (parallel, crossover, titration) 6. What are the questions relating to clinical trials? Does it work? How well does it work?What are the questions relating to clinical trials?== Does it work? How well does it work? 7. How do you measure if a drug works? Comparison, methodHow do you measure if a drug works?== Comparison, method 8. How do you measure how well a drug works? Size of response, methodsHow do you measure how well a drug works?== Size of response, methods 9. What are the other types of analysis? Model, powerWhat are the other types of analysis? ==Model, power 10. What does power test? Reliability of the trial (number of subjects etc)What does power test? ==Reliability of the trial (number of subjects etc) 11. What is analysis perpective? Intention to treat, as treatedWhat is analysis perpective?== Intention to treat, as treated Loading...
