Lecture 26

1.
What is tissue resulting from neoplasia called?= =Neoplasm
2.
Why is neoplasia not reversible?
Abnormal differentiation, lack of control, immortalilty
3.
What reveals neoplasia most?
Abnormal differentiation, abdormal function, altered communication
4.
What are blood markers for neoplasia?
Beta proteins 
5.
What cancer is more common in women?
Breast
6.
Which cancer is more common in men?
Prostate
7.
What is benign behaviour?
Grows within tissue but does not invade and destroy
8.
What is malignant behaviour?
Invades, spreads, destroys, looks like tissue
9.
What is distinctive about epithelial malignant neoplasia?
Destruction of basement membrane and adjacent tissues, ulceration
10.
How is malignant spread facilitated?
In lymph or blood
11.
What does metastasis cause?
Secondary tumours
12.
What are the classifications of neoplasms?
Epithelial, stromal, lymphoid/haematopoietic
13.
What is the suffix for benign tumours?
-oma
14.
What is the suffix for epithelial malignant neoplasm?
-carcinoma
15.
What is the suffix for malignant connective tissue neoplasia?
Sarcoma
16.
What is a benign tumour originating in  secreting epithelium?
Adenoma
17.
What is a malignant tumour originating in  secreting epithelium?
Adenocarcinoma
18.
19.
What is a malignant tumour originating in  protective epithelium?
Squamous cell carcinoma
20.
What is a malignant tumour originating in  basement epithelium?
Basal cell caricnoma
21.
What observations define malignant tumours?
Rough edge, ulcerated, different tissue
22.
What do you call a malignant tumour of fibrous tissue?
Fibrosarcoma
23.
What do you call a malignant tumour of the nerve sheath?
Neurofibrosarcoma
24.
What do you call a malignant tumour of adipose tissue?
liposarcoma
25.
What do you call a malignant tumour of smooth muscle tissue?
Leiomyosarcoma
26.
What do you call a malignant tumour of striated muscle tissue?
Rhabdomyosarcoma
27.
What do you call a malignant tumour of cartilaginous tissue?
Chondrosarcoma
28.
What do you call a malignant tumour of bone tissue?
Osteosarcoma
29.
What cancer is malignant neoplasia of plasmacells?
Multiple myeloma
30.
31.
What cancer is malignant neoplasia of progenitor cells of WBCs?
Leukaemia
32.
What cancer is malignant neoplasia of male germ cells?
Seminoma testicular cancer
33.
What cancer is benign neoplasia of female germ cells?
Dermoid cysts, cystic teratomas
34.
What is a blastoma?
Stem cell neoplasia in children
35.
What are the steps to metastasis?
Invade, embolize, extravasation
36.
What are clinical signs of metastasis?
Palpable lymph nodes, bone pain
37.
What is transcoelomic spread?= =Penetration of cavity linings
38.
Why do lymph nodes firm up?
Filter and catch metastasis
39.
What are the stages of spread?
Tis - in situ, T1 - microinvasion, T2 - local invasion, T3 - secondary invasion, T4 - extensive invasion
40.
What do T, N, M stand for in neoplasm staging?
Tumour, lymph node, metastasis
41.
"What is gauged in ""tumour""?"
Size and invasiveness of tumour
42.
"What is gauged in ""lymph""?"
Lymph node involvement
43.
What is gauged in metastasis?
No metastases or distant metastases