Lecture 26

1.
What are the most common bacterial infections of the liver?
Gallbladder choleystitis, bile duct cholangitis 
2.
How does the gall blader become infection?
Bacteria from faecal matter matter travel from duodenum to bile ducts => cystic ducts => gallbladder
3.
How is hepatitis A contracted?
Faeces 
4.
What is the source of infection for Heb B?
Blood
5.
How is Heb B transmitted?
Sex, needles, birth
6.
How is Hep C transmitted?
Needles
7.
Which hepatitis viruses have a vaccine?
A, B
8.
What is the mortality for Hep A?
1%
9.
What is mortality of Hep B?
10%
10.
What is the mortality for Hep C?
0.1%
11.
What is the diagnostic technique for Heb B?
Blood test
12.
What is tested for in a Hep B bloodtest?
HBsAg
13.
What are the components of HBV?
HBsAg, HBcAg, DNA
14.
What does the HBV dirct hepatocytes to secrete?
HBsAg
15.
What determines risk of HBV infection?
Concentration of HBV
16.
What is a test for infectivity?
HBeAg
17.
How much more infective is someone who is HBeAg+?
10x more
18.
How is HBV cleared?
Cytotoxic lymphocytes
19.
What causes damage to the liver?
Immune response
20.
What provides immunity to the HBsAg?
HBgAb
21.
What are the characteristics of infant HBV infection?
Insufficient immune response to clear virus, persistant infection, ongoing attack and liver cell destruction => cirrhosis, liver cancer
22.
What is a treatment for HBV? Injection of antibodies to HBeAg