Lecture 24

1.
What repiratory cells do viruses infect?
Goblet, epithelial
2.
What are the symptoms of respiratory tract virus infections?
Narrowed airways, obstructed airways, viscous mucous, stem cells
3.
Why are respiratory tract viral infections particularily severe for young children?
Already narrow airways - thickening mucosa obstruction
4.
List the respiratory infections in NZ in order of commonality?
Cold, flu, bronchitis, pneumonia, TB
5.
What are common bacteria for respiratory tract infections?
S. pyongenes, S. pneumoniae
6.
What are common viruses for respiratory tract infections?
Rhinovirus, coronavirus, flu, RSV
7.
Which illnesses are almost always viral?
Colds, bronchitis, pharangitis, influenza
8.
Which size aerosols can be blocked by surgical masks?
>10 micrometers
9.
Which size can only be filtered by N95 filters?
<10 microns
10.
How can larger droplets cause lung infections?
Infection in upper respiratory tract aspirated down
11.
What antibodies are produced in covid 19?
IgM, IgA, IgG
12.
What does haemagluttinin look like?
Cone (trimer)
13.
What does neuraminadase look like?
Hammer (tetramer)
14.
What is gradual variation of infectious viruses?
Genetic drift
15.
What is abrupt variation of infectious viruses?
Genetic shift
16.
What causes drift?
Accumulation of mutations
17.
What causes shift?
recombination
18.
What are the best tests for flu?
PCR, antibody, clinical presentation