Lecture 23

1.
What are the characteristics of viruses?
Cannot make proteins or energy, do not replicate by division (assembled), require host
2.
How are viruses classified?
Structure, made of replication, disease, transmission, host cell, tissue/organ, family, location
3.
What are the components of a virus?
DNA/RNA, capsid, envelope, cellular glycoproteins
4.
Describe the capsid assembly?
Polyhedral, helical, naked
5.
What is the naked capsid stable to?
Temperature, acid, detergent, drying, proteases
6.
What is the envelope virus stable to?
Acid, detergent, drying, heat
7.
8.
What are the steps to the growth cycle of a virus?
Attachment, infection, latency, production
9.
What generates mRNA from DNA?
DNA dependent RNA polarmerase
10.
What generates mRNA from +RNA?
RNA dependent RNA
11.
Where does the virus obtain RNA polymerase
RNA => ribosomes => -RNA => ribosomes => +RNA => RNA polymerase => mRNA
12.
Where does the virus obtain RNA polymerase?
Carried by virus => mRNA
13.
What is the progression of viral disease?
Acquisition, infection, incubation, replication, immune response, elimination and persistance
14.
How are viruses transmitted?
Airborne, food/water, fomites, direct contact, maternal neonatal, zoonosis
15.
What are examples of latent viral infections?
HIV, herpes, varicella
16.
What are the examples of oncogenic viruses?
HPV, epstein-barr virus, herpes
17.
What are even simpler than viruses?
Viroid (plants), prions (neurological diseases)