HomeCoursesMEDSCI 202: Microbiology and ImmunologyLecture 16 Lecture 16 1. Which cells secrete antibodies? B cellsWhich cells secrete antibodies?== B cells 2. Which is the largest antibody molecule? IgMWhich is the largest antibody molecule?== IgM 3. What type of antibody are IgM? AggluttinatorsWhat type of antibody are IgM?== Aggluttinators 4. What characteristic makes it IgM a powerful contributor to the immune system? Efficient complement activatorWhat characteristic makes it IgM a powerful contributor to the immune system? ==Efficient complement activator 5. How much of the immonglobulin pool is made up of IgM? 10%How much of the immonglobulin pool is made up of IgM? ==10% 6. What is the most common immunoglobulin? IgG (75%)What is the most common immunoglobulin? ==IgG (75%) 7. How does IgG contribute to the immune response? (4)= =Antitoxin, opsin, barrier, complement activator How does IgG contribute to the immune response? (4)= =Antitoxin, opsin, barrier, complement activator 8. How much of the immunolgical pool is made up of IgA? 20%How much of the immunolgical pool is made up of IgA?== 20% 9. Where is IgA found? Sero-mucous secretionsWhere is IgA found?== Sero-mucous secretions 10. What type of polymer is IgA? DimericWhat type of polymer is IgA?== Dimeric 11. What type of polymer is IgG? MonomericWhat type of polymer is IgG?== Monomeric 12. What type of polymer is IgM? 5x polymerWhat type of polymer is IgM?== 5x polymer 13. How does IgA contribute to the immune system/ As a barrierHow does IgA contribute to the immune system/== As a barrier 14. Where is IgD found? Surface of naive B cellsWhere is IgD found?== Surface of naive B cells 15. What is the function of IgD?= Triggers to antigen to activate B cells 16. Which immunoglobulin is responsible for allergies? IgEWhich immunoglobulin is responsible for allergies?== IgE 17. What cells does IgE activate? Mast cellsWhat cells does IgE activate?== Mast cells 18. What are humoral immunity characteristics? (3) Product of B cells, is made up of antibodies, effective against extracellular antigensWhat are humoral immunity characteristics? (3)== Product of B cells, is made up of antibodies, effective against extracellular antigens 19. What makes the T cell receptor complex? (3) CD3 + TCR + either CD4 or CD8What makes the T cell receptor complex? (3)== CD3 + TCR + either CD4 or CD8 20. What do cytotoxic T cells recognise? (2) MHC1 + peptideWhat do cytotoxic T cells recognise? (2)== MHC1 + peptide 21. What do helper T cells recognise? (2)== MHC 2 + peptide 22. What type of cell presents MHC 1? Target (virus infected) cellWhat type of cell presents MHC 1?== Target (virus infected) cell 23. What type of cell presents MHC 2? Antigen presenting cellsWhat type of cell presents MHC 2?== Antigen presenting cells 24. What are the types of class 1 HLA? (3) HLA-A, HLA-B, HLA-CWhat are the types of class 1 HLA? (3)== HLA-A, HLA-B, HLA-C 25. What are the classes of class II HLA?== HLA-DP, HLA-DQ, HLA-DR 26. Where are the MHC 1 molecules found? All nucleated cellsWhere are the MHC 1 molecules found?== All nucleated cells 27. What do class 1 MHC cells present to? CD8 T cellsWhat do class 1 MHC cells present to?== CD8 T cells 28. Where are MHC 2 molecules found? (2) B cells, APCsWhere are MHC 2 molecules found? (2)== B cells, APCs 29. What do MHC2 present to? CD4 T cellsWhat do MHC2 present to? == CD4 T cells 30. When does an MHC 1 APC/B cell present non self antigens to CD8 T cells? (2) When infected with a virusWhen does an MHC 1 APC/B cell present non self antigens to CD8 T cells? (2)== When infected with a virus 31. When does an MHC II present peptide antigens? After phagocytosis of antigenic materialWhen does an MHC II present peptide antigens?== After phagocytosis of antigenic material 32. What happens when an MHC1 cell presents to CD8 T cells in lymph nodes? Activates T cellWhat happens when an MHC1 cell presents to CD8 T cells in lymph nodes?== Activates T cell 33. What does activation of T cell allow for? CD4 cell factors (eg. IL-2) stimulate proliferationWhat does activation of T cell allow for?== CD4 cell factors (eg. IL-2) stimulate proliferation 34. What does proliferation result in? (2) Memory cells, CD 8 T cellsWhat does proliferation result in? (2)== Memory cells, CD 8 T cells Loading...
