Lecture 17

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Question 1 of 31

What does it mean to say epithelial cells are ‘polarised’?= Permeability and structure differences between apical and basolateral membranes

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Question 2 of 31

What proteins form the apical junctional complex? (4)= Zonula occudins (tight junctions), zonula adherins (adherins junctions), gap junctions, macula adherins (desmosomes)

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Question 3 of 31

What do zona occludans interact with?= Actin proteins in the cytoskeleton

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Question 4 of 31

What do zona adherins (intermediate/adherens junctions) bind to?= Cadherins bind adjacent cell membranes, catenin binds actin terminal web

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Question 5 of 31

What filaments do desmosomes bind?= Intermediate filaments

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Question 6 of 31

Which proteins do gap junctions use?= Connexons (connexin proteins)

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Question 7 of 31

Which junctions form belts around the cells?= Cadherens/intermediate junctions

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Question 8 of 31

Which juctions facilitate communication between cells?= Gap junctions

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Question 9 of 31

What are the regions of the basement membranes of epithelial cells? (2)= Basal lamina, basal reticular

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Question 10 of 31

What layers does the basal lamina divide into? (2)= Lamina lucida, lamina densa (basal lamina)

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Question 11 of 31

What is the lamina propria?= Loose irregular connective tissue

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Question 12 of 31

What proteins are used by the reticula lamina? (2)= Collagen fibres, fibronectin

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Question 13 of 31

What are the proteins of the lamina lucida? (2)= Laminin, integrins (of hemidesmosomes)

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Question 14 of 31

What are the proteins of the lamina densa? (2)= Laminin, collagen IV

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Question 15 of 31

What adheres the lamina lucida to the epithelial cells?= Hemidesmosomes

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Question 16 of 31

What proteins do hemidesmosomes use?= Integrins

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Question 17 of 31

What do hemidesmosomes bind to?= Intermediate filaments

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Question 18 of 31

What are some apical specialisations of epithelia? (3)= Microvilli, stereocilia, cilia

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Question 19 of 31

What is glycocalyx?= Thick layer containing digestive enzymes that covers intestinal microvilli

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Question 20 of 31

What part of the actin skeleton is connected to microvilli?= Terminal web

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Question 21 of 31

What occupies the internal space of cilia?= Contractile cytoskeleton

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Question 22 of 31

What occupies the internal space of the microvilli?= Actin filaments

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Question 23 of 31

What are the main functions for microvilli?= Increase apical surface area of epithelial cells to increase absorption/secretion

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Question 24 of 31

What are the main functions for cilia?= Movement of substances along the lumen of the cavity they line

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Question 25 of 31

What is the main function of stereocilia?= Increase absorption surface area in epididymus and vas deferens

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Question 26 of 31

What are the types of glands? (2)= Exocrine, endocrine

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Question 27 of 31

What makes an exocrine gland different from an endocrine?= Exocrine excrete into ducts, endocrine excrete into blood

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Question 28 of 31

What are the types of simple epithelial glands? (5)= Tubular, coiled tubular, branched tubular, alveolar, branched alveolar

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Question 29 of 31

What are the types of compound glands? (3)= Compound tubular, compound alveolar, compound tubuloalveolar

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Question 30 of 31

What are serous glands?= Exocrine glands that secrete watery substances

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Question 31 of 31

What are the modes of secretion? (3)= Merocrine (vesicles), apocrine (cytoplasm excretion), holocrine (lysis)

Question 31 of 31