Lecture 26

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Question 1 of 31

What makes up the total volume? = Vt : VA + Vd.

Question 1 of 31

Question 2 of 31

What makes up the alveolar volume? = Vt – Vd 2Va.

Question 2 of 31

Question 3 of 31

What is the equation for rate of change of alveolar volume? = VA : Fr (VE – Vd).

Question 3 of 31

Question 4 of 31

How does this differ from the rate of inspiration? = VA : ⅔ Vt.

Question 4 of 31

Question 5 of 31

What is normal CO2 – O2 exchange rates? = 0.8 CO2 : O2 (respiratory exchange rate).

Question 5 of 31

Question 6 of 31

What is the PCO2 when VA is around GL min-1? = 40 mmHg.

Question 6 of 31

Question 7 of 31

What happens to PCO2 during hypoventilation? = Increases.

Question 7 of 31

Question 8 of 31

What is the PO2 when ____ is around 4 L min-1? = 10 mmHg.

Question 8 of 31

Question 9 of 31

What is the maximum PO2 during hyperventilation? = 150 mmHg.

Question 9 of 31

Question 10 of 31

During control of ventilation: (I) What is regulated? (II) What is sensed? (III) Where is it sensed? = (I) Breathing rate. (II) O2, CO2, pH. (III) Aorta, carotid artery, medulla oblongata.

Question 10 of 31

Question 11 of 31

What is the resting rate of consumption? = 300mL min-1.

Question 11 of 31

Question 12 of 31

What is the concentration of O2 in F R C? = 300mL.

Question 12 of 31

Question 13 of 31

What is the normal size of F R C? = 2.5L.

Question 13 of 31

Question 14 of 31

What is the content O2 of F R C? = 300mL.

Question 14 of 31

Question 15 of 31

How much is stored as HbO2? = 900mL.

Question 15 of 31

Question 16 of 31

What is the max anoxic survival time? = 4 min.

Question 16 of 31

Question 17 of 31

Which does the respiratory system react to most – PO2, PCO2 or pH? = PCO2.

Question 17 of 31

Question 18 of 31

Where is PCO2 sensed in the periphery? (2) = Carotid bodies, aortic bodies.

Question 18 of 31

Question 19 of 31

Which nerves do they utilise? (2) = IX, X.

Question 19 of 31

Question 20 of 31

Where is it sensed in the CNS? = Ventral oblongata medulla.

Question 20 of 31

Question 21 of 31

Where is pH sensed? = Ventral oblongata medulla.

Question 21 of 31

Question 22 of 31

What products do CO2 and H2O form? = CO2 + H2O → H2CO3 + → HCO3 - + H+.

Question 22 of 31

Question 23 of 31

How does medulla sense pH? = CO2 → CSF → blood brain barrier → H+ → medulla.

Question 23 of 31

Question 24 of 31

Why is the system unresponsive to O2 reduction during hypervent? = As we breathe faster CO2 ↓ which is the main ingredient for response.

Question 24 of 31

Question 25 of 31

What happens if CO2 is constant and O2 is reduced? (40mmHg). = Breathing rate skyrockets.

Question 25 of 31

Question 26 of 31

What effect does increase in CO2 have on rate of respiration? = Increase.

Question 26 of 31

Question 27 of 31

What happens if O2 is kept constant at 110mmHg / 40mmHg? = 150mmHg increase. 40 mmHg vast increase.

Question 27 of 31

Question 28 of 31

What are involuntary movements for breathing? (5) = Coughing, breathing, sighing, expectoration, thoracic stabilisation.

Question 28 of 31

Question 29 of 31

What might be the reason for sighing? = Open closing alveoli.

Question 29 of 31

Question 30 of 31

What are voluntary breathing movements? (4) = Singing, ventilation, parturition (uterine pressure during childbirth), defecation.

Question 30 of 31

Question 31 of 31

What are the regulatory bodies of respiration? = DRG, → inspiration VRG – inspiration and expiration.

Question 31 of 31